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KMID : 1155520140090020115
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Anesthesia and Pain Medicine
2014 Volume.9 No. 2 p.115 ~ p.118
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Probable tramadol-induced atypical serotonin syndrome in a patient receiving selective serotonin reuptake inhibitor and stopped at 10 days before surgery -A case report-
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Kang Yoo
Min Jin-Hye
Chae Young-Keun
Lee Sang-Eun
Je Ui-Jin
Lee Yong-Kyung
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Abstract
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Tramadol can increase the serum level of serotonin, causing serotonin syndrome, which is a potentially life-threatening condition. Serotonin syndrome occurs when tramadol is used in combination with other drugs that affect serotonin. A patient who had been taking selective serotonin reuptake inhibitor and stopped at 10 days before surgery experienced intermittent heart rate elevation, tremor of the upper extremities and mental change after receiving an infusion of tramadol for postoperative pain control. Although he did not show the typical triad of serotonin syndrome (systemic autonomic dysfunction, neuromuscular impairment and mental status change), the patient was suspected to have serotonin syndrome caused by tramadol.
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KEYWORD
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Postoperative pain control, Selective serotonin reuptake inhibitors, Serotonin syndrome, Tramadol
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Listed journal information
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